Strain Information | |
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Image | |
BRC No. | RBRC04495 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(Tek-cre)1Ywa |
Former Common name | Tie2-Cre, B6-TekCre Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Masashi Yanagisawa, The University of Texas Southwestern Medical Center. Mixed background. |
Strain description | Tek-cre (Tie2-cre) transgenic mice. These mice express a cre recombinase gene under the control of the mouse Tek promoter. |
Colony maintenance | Carrier x Noncarrier [or Crossing to C57BL/6N(Crlj)] |
References | Dev. Biol., 230, 230-242 (2001). 11161575 J. Clin. Invest., 108, 537-546 (2001). 11518727 |
Health Report | |
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Examination Date / Room / Rack | 2024/01/09Room:3-ARack:G 2023/10/16Room:3-ARack:G 2023/10/10Room:3-ARack:G 2023/07/10Room:3-ARack:G 2023/04/10Room:3-ARack:G 2023/02/13Room:3-ARack:G 2023/01/10Room:3-ARack:G 2022/10/11Room:3-ARack:G 2022/07/11Room:3-ARack:G 2022/04/11Room:3-ARack:G |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Mt1mouse metallothionein-1(MT-1) polyA signalUNMt1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinaseUNcretransgene insertion 1, Masashi Yanagisawamouse endothelial-specific receptor tyrosine kinase promoter |
Ordering Information | |
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Donor DNA | mouse Tie2 promoter, Phage P1 Cre, mouse metallothionein-1(MT-1) poly A signal, mouse Tie2 intron 1 enhancer |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Biol., 230, 230-242 (2001). Depositor limits the use of the BIOLOGICAL RESOURCE to not-for-profit institutions. Depositor limits the use of the BIOLOGICAL RESOURCE to academic purposes. For-profit institutions and recipients who intend to use BIOLOGICAL RESOURCE for commercial research purposes shall acquire prior written consent from the Depositor. Recipient shall acquire prior written consent from the Depositor prior to filing an application for patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE. |
Depositor | Masashi Yanagisawa (University of Texas Southwestern Medical Center at Dallas) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering:
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BRC mice in Publications |
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Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A. Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep 29(3) 603-616.e5(2019) 31618630 Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, Murohara T, Kato K, Sundaram S, Stanley P, Okajima T. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. Elife 6 (2017) 28395734 Kakae M, Nakajima H, Tobori S, Kawashita A, Miyanohara J, Morishima M, Nagayasu K, Nakagawa T, Shigetomi E, Koizumi S, Mori Y, Kaneko S, Shirakawa H. The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production. Sci Adv 9(29) eadh0102(2023) 37478173 |