Strain Data Sheet
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Data update: May 20, 2019
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RBRC No. RBRC04738  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(Lck-cre)1Jtak  
Former Common name Lck-cre Tg mouse  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Dr. Junji Takeda, Research Institute for Microbial Diseases, Osaka University (Eur J Immunol. 1998 28 (7) : 2159-2166).  
Strain description This transgenic mice express the cre-recombinase under the control of the Lck proximal promoter.  
Colony maintenance Heterozygote x Wild-type [C57BL/6J]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol GH  
Symbol name Growh hormone polyA (human)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter lck proximal promoter  
 2 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References J Immunol. 2008 Mar 15;180(6):3746-56.
  
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.  
Additional information
 1 Takeda Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Takeda, Junji (Osaka University)  Takeda, Junji 
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