Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Aug 20, 2019
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RBRC No. RBRC04739  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.B6CB-Ltb4r1<tm1Tksh>  
Former Common name B6-BLT1 KO  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Dr. Takao Shimizu, Faculty of Medicine, University of Tokyo in 2005. A lacZ-neo was inserted into exon 2 of the Ltb4r1 gene (Expression of lacZ was not detected). The mutant mice were backcrossed to C57BL/6.  
Strain description No Data  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Ltb4r1  
Symbol name leukotriene B4 receptor 1  
Chromosome 14  
Common name No Data  
Symbol description No Data  
References J Immunol 2005 Oct 1;175(7):4217-25.
Nature. 1997 Jun 5;387(6633):620-4.



  
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Absence of leukotriene b4 receptor 1 confers resistance to airway hyperresponsiveness and th2-type immune responses.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Immunol., 175, 4217-4225 (2005).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Shimizu, Takao (The University of Tokyo, Graduate School of Medicine)  Shimizu, Takao 
Strain Status /
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