Strain Information | |
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Image | |
BRC No. | RBRC04797 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6;B6C3(129)-Tg(NDE-hsp-Pkd2*D509V,lacZ)3Hmd |
Former Common name | NDE-m2Pkd2-lacZ Tg#3 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Dr. Satoko Yoshiba and Dr. Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2008. Transgene was injected into the pronuclei of B6C3F1 fertilized eggs. |
Strain description | This transgenic mouse strain expresses the Asp509Val variant Pkd2 and lacZ on both node under the control of the mouse node-specific enhancer. |
Colony maintenance | Carrier X Noncarrier [C57BL/6JJcl] |
References | Science, 338, 226-231 (2012). 22983710 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)UNinternal ribosomal entry site from EMCV Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Pdk2pyruvate dehydrogenase kinase, isoenzyme 2UNPdk2mouse node-specific enhancer, hsp promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)UN |
Ordering Information | |
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Donor DNA | マウス由来Nodalのノードエンハンサー, Pkd2cDNA, hspプロモーター, E. coli由来 LacZ遺伝子, ウィルス由来 IRES配列 |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science, 338, 226-231 (2012). |
Depositor | Hiroshi Hamada (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |