Strain Information | |
---|---|
Image | |
BRC No. | RBRC04849 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.B6CB-Ptges2<tm1> |
Former Common name | Membrane-associated prostaglandin E2 synthase-2 (mPGES2) KO, B6.B6CB-Ptges2<tm1> |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Kikuko Watanabe, University of East Asia Guraduate School of Integrated Science and Art Division of Medical and Life Science. |
Strain description | |
Colony maintenance | Heterozygote x Wild-type [C57BL/6J(Crlj)] Homozygous mutant mice are viable and fertile. |
References | Nat. Immunol., 14(6):554-63 (2013). 23624557 Biochem. Biophys. Res. Commun., 341, 132-138 (2006). 16414015 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site2Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)2internal ribosomal entry site from EMCV Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)2neo; neomycin; |
Ordering Information | |
---|---|
Donor DNA | mouse PGES2 genomic DNA, E. coli neomycin resistance gene, E. coli beta-galactosidase gene, mouse En-2 gene splice acceptor, EMCV internal ribosomal entry site, SV40 PolyA signal, P1 Phage loxP, yeast FRT (flipase recombination target) site |
Research application | Cre/loxP system FLP/frt system Fluorescent Proteins/lacZ System Immunology and Inflammation Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from use of the BIOLOGICAL RESOURCE. |
Depositor | Motonao Nakamura (The University of Tokyo) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |