Strain Information | |
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Image | |
BRC No. | RBRC04905 |
Type | Targeted Mutation and Transgene |
Species | Mus musculus |
Strain name | C;129P2(Cg)-Cxcr4<tm1Yiw> Tg(Lck-cre)1Jtak |
Former Common name | C.129P2(Cg)-Cxcr4<tm1Yiw> Tg(Lck-cre)1Jtak |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Cxcr4 floxed mice were developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2010. Lck-cre Tg mice were developed by Junji Takeda, Osaka University in 1998. Double mutant mice were backcrossed BALB/c for at least 8 times. |
Strain description | Cxcr4 floxed mice with Lck-cre transgene. |
Colony maintenance | |
References | Arthritis Res. Ther., 12, R188 (2010). 20939892 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)1neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinaseUNcremouse lck promoter |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, mouse Cxcr4 genomic DNA, mouse Lck promoter, phage P1 Cre recombinase gene |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Res. Ther., 12, R188 (2010). Eur. J. Immunol., 28(7):2159-2166 (1998).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. |
Depositor | Yoichiro Iwakura (The University of Tokyo) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |