Strain Data Sheet

RBRC04923

Strain Information

Image
BRC No.RBRC04923
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC3.129X1-Ifng<tm1Yiw>
Former Common name
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1997. The mice were backcrossed to C3H for at least 8 times by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo.
Strain descriptionIFN gamma knockout mice. Homozygous mutant mice show increased susceptibility to infection.
Colony maintenance
ReferencesJ. Immunol., 159, 1418-1428 (1997). 9233639

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ifnginterferon gamma10Ifng<tm1Yiw>targeted mutation 1, Yoichiro Iwakura

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)10neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

Donor DNANeomycin resistance gene, lacZ gene (E. coli), PolyA signal (SV40), MC1 promoter (HSV)
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Immunol., 159(3):1418-1428 (1997).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data