Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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  Mouse Marking
Figure
  Order
RBRC No. RBRC05065  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.B6CB-Sox1<tm1(cre)Take>  
Former Common name B6-Sox1/cre KI  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Cre recombinase was inserted into the ATG codon start site if Sox1 by in-frame. PGK-neo cassette was removed by Flp recombinase expression.  
Strain description Sox1 cre knock-in mice. knocked into the Sox1 gene. No obvious defect at the heterozygous state which is used for the conditional KO or cell tracing purposes.  
Colony maintenance Heterozygote X Wild-type [C57BL/6NJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Sox1  
Symbol name SRY-box containing gene 1  
Chromosome 8  
Common name No Data  
Symbol description No Data  
 2 Symbol Frt  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome 8  
Common name No Data  
Symbol description No Data  
 3 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome 8  
Common name No Data  
Symbol description No Data  
References Cell. 2007 Jun 29;129(7):1377-88.  
Neuroepithelial cells supply an initial transient wave of MSC differentiation.
Research applications Cre/loxP system,
FLP/frt system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0525K, and Web Site (http:www.cdb.riken.jp/arg/mutant%20mice%20list.html) and the BIOLOGICAL RESOURCE is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Cell, 129, 1377-1388 (2007).)  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology)  RIKEN, CDB 
Strain Status /
Availability
(Expected delivery)

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