Strain Data Sheet

RBRC05263

Strain Information

Image
BRC No.RBRC05263
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6.DW-Tpst2<grt>/Hkv
Former Common nameB6-grt
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Nobuya Sasaki and Takashi Agui, Graduate School of Veterinary Medicine, Hokkaido University in 2010. Tpst2<grt> allele derived from DW/J-Tpst2<grt> was backcrossed to C57BL/6JJcl for 14 generations.
Strain descriptionTpst2<grt> B6 congenic strain. Homozygous mutant mice show a delayed pubertal growth and hypothyroidism. Homozygous females are infertile and males show markedly-decreased fertility.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesJ. Vet. Med. Sci., 70, 1043-1049 (2008). 18981659
Biomed. Res. 31, 207-211 (2010). 20622471
Mol. Endocrinol., 21, 1713-1721 (2007). 17456791

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tpst2protein-tyrosine sulfotransferase 25Tpst2<grt>protein-tyrosine sulfotransferase 2; growth retarded

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
DepositorTakashi Agui (Hokkaido University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data