Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Apr 19, 2019
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RBRC No. RBRC05281  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name LtbR (Acc. No. CDB0531K)  
Former Common name No Data  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Mitsuru Matsumoto, Institute for Enzyme Research, The University of Tokushima.  
Strain description Lymphotoxin B receptor knockout mice. Homozygous mutant miceexhibit accumulation of lymphoid cell aggregates (B220+, CD4+, and CD8+ lymphocytes) in the liver and lung.  
Colony maintenance Heterozygote x Wild-type [C57BL/6N]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Ltbr  
Symbol name lymphotoxin B receptor  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome No Data  
Common name neo; neomycin;  
Symbol description No Data  
 3 Symbol Frt  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
 4 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
 5 Symbol lox71  
Symbol name mutant lox sequence  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
 6 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome No Data  
Common name No Data  
Symbol description No Data  
References   
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Mitsuru Matsumoto, The University of Tokushima, E-mail: mitsuru@ier.tokushima-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0531K and Web. Site (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Immunol. 2011 186(9):5047-57.) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.  
Additional information
 1 Mouse of the Month Oct 2013  
 2 Genotyping protocol <PCR>  
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology)  RIKEN, CDB 
Strain Status /
Availability
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