Strain Information | |
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Image | |
BRC No. | RBRC05285 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Crtac1<tm1Kota>/Rbrc |
Former Common name | Crtac1(-) (Acc. No. CDB0599K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Kohtaro Takei, Yokohama City University Graduate School of Medicine. |
Strain description | Crtac1, cartilage acidic protein 1 knockout mice. The first exon of Crtac1 was replaced with loxP-neo-loxP cassette. Homozygous mutant mice show abnormal olfactory morphology. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6N] |
References | Science, 333, 769-773 (2011). 21817055 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP19loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)19neo; neomycin; |
Ordering Information | |
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Donor DNA | E. coli neo, phage P1 loxP, mouse phosphoglycerate kinase promoter (PGK promoter), mouse PGK3’end, mouse Crtac1 genomic DNA |
Research application | |
Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Kohtaro Takei, Yokohama City University, E-mail: kohtaro@med.yokohama-cu.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0599K and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Science. 2011 333(6043):769-73.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |