Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC05362  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.Cg-Fah<tm1Sia>/Rbrc  
Former Common name FAH(-) (Acc. No. CDB0201K)  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Shinichi Aizawa, RIKEN Center for Developmental Biology.  
Strain description Fah, fumarylacetoacetate hydrolase knockout mice.  
Colony maintenance Heterozygote x Wild-type [C57BL/6N]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Fah  
Symbol name fumarylacetoacetate hydrolase  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
References Hepatology. 2008 Dec;48(6):1964-78.  
Flow cytometric isolation and clonal identification of self-renewing bipotent hepatic progenitor cells in adult mouse liver.
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0201K and Web. Site (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html) is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Hepatology. 2008 48(6):1964-78.) (3) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology)  RIKEN, CDB 
Strain Status /
Availability
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