Strain Information | |
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Image | |
BRC No. | RBRC05427 |
Type | Transgene |
Species | Mus musculus |
Strain name | 129.B6C3-Tg(Dkk3-cre)D9Tfur |
Former Common name | 129-Dkk3-cre Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2007. The transgene was injected into the B6C3F1 fertilized eggs. The transgenic mice were backcrossed to 126S6 mice over 8 generations. |
Strain description | This transgenic mouse expresses Cre recombinase gene under the control of the 12-kb mouse Dkk3 promoter. Cre activity is detectable from embryonic day 10.5 (E10.5) and generally restricted to the retina during embryogenesis. |
Colony maintenance | Carrier x Noncarrier [or Crossing to 129S6/SvEvTac] |
References | Genesis, 45, 502-507 (2007). 17661397 |
Health Report | |
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Examination Date / Room / Rack | 2023/09/11Room:3-3Rack:B 2023/06/13Room:3-3Rack:B 2023/03/13Room:3-3Rack:B 2022/12/12Room:3-3Rack:B 2022/09/12Room:3-3Rack:B 2022/06/13Room:3-3Rack:B 2022/05/16Room:3-3Rack:B |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinaseUNcre<Tg(Dkk3-cre)D9Tfur>transgene insertion D9, Takahisa Furukawamouse DKK3 promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signalUN |
Ordering Information | |
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Donor DNA | BAC clone RP23-12M6 containing mouse DKK3 genomic DNA, P1 Phage Cre recombinase, SV40 PolyA signal, Phage P1 loxP derived from pBACe3.6 vector |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genesis. 45, 502-507 (2007).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University). |
Depositor | Takahisa Furukawa (Osaka Bioscience Institute) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |