Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC05446  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6(129)-Tg(Plp1-tTA)1Ike  
Former Common name PLP-tTA Tg, B6-PLP-tTA Tg  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kenji Tanaka, National Institute for Physiological Sciences. The transgene was injected into the pronuclei of C57BL/6J fertilized eggs. C57BL/6 and 129 mixed background.  
Strain description PLP-tTA transgenic mice. These transgenic mice express tetracycline-controlled transactivator (tTA) gene under the control of the mouse PLP promoter. tTA expression is detected in oligodendrocytes.  
Colony maintenance Carrier x Noncarrier [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol No Data  
Symbol name SV40 polyA signal  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse PLP promoter  
 2 Symbol tTA  
Symbol name tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)  
Chromosome UN  
Common name E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain  
Symbol description No Data  
References   
Research applications Tet system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature designated by the DEPOSITOR is requested. [Htr5B-tTA KI: (will be announced), PLP-tTA Tg: Genesis.2011 Sep 22. doi:10. 1002/dvg. 20808.] The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit organization for a not-for-profit research. Prior to requesting the BIOLOGICAL RESOURCE, RECIPIENT must inform the DEPOSITOR of his project using the Approval Form. If the
use of this BIOLOGICAL RESOURCE results in scientific publications, the RECIPIENT should cite Kenji F. Tanaka as co-author in the first paper.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Tanaka, Kenji (Keio University)  Tanaka, Kenji 
Strain Status /
Availability
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