Strain Data Sheet
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Data update: May 20, 2019
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RBRC No. RBRC05450  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6;CBB6(129)-Tg(Mlc1-tTA)2Rhn  
Former Common name Mlc1-tTA#2, B6-Mlc1-tTA Tg#2  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kenji Tanaka, Columbia University in 2007. C57BL/6 and 129S6 mixed background.  
Strain description Mlc1-tTA transgenic mice. These transgenic mice express tetracycline-controlled transactivator (tTA) gene under the control of the mouse Mlc1 promoter. tTA expression is detected in Mlc1 positive astrocytes.  
Colony maintenance Carrier x Noncarrier [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol No Data  
Symbol name SV40 polyA signal  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse Mlc1 promoter  
 2 Symbol tTA  
Symbol name tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)  
Chromosome UN  
Common name E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain  
Symbol description No Data  
References   
Research applications Tet system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biol. Psychiatry, 67, 770-773 (2010).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Tanaka, Kenji (Keio University)  Tanaka, Kenji 
Strain Status /
Availability
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