Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC05501  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name 129-Tmem119<tm1Tfur>  
Former Common name 129-Obif KO, 129-Obif<tm1Tfur>  
H-2 Haplotype No Data  
ES cell line TC1 [129S6/SvEvTac]  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2006. 129 background.  
Strain description Obif, osteoblast induction factor gene knockout mice. Exon 2 of Obif gene was replaced with PGK-neo cassette. Homozygous mutant mice show lower bone mass than controls at 14 days and 8 weeks old.  
Colony maintenance Homozygote x Heterozygote [or Crossing to 129S6/SvEvTac]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Tmem119  
Symbol name transmembrane protein 119  
Chromosome 5  
Common name obif  
Symbol description No Data  
 2 Symbol No Data  
Symbol name SV40 Poly A signal  
Chromosome 5  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 5  
Common name neo; neomycin;  
Symbol description No Data  

Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Dev. Growth Differ., 54(4):474-480 (2012).
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Furukawa, Takahisa (Osaka Bioscience Institute)  Furukawa, Takahisa 
Strain Status /
(Expected delivery)

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