Strain Information | |
---|---|
Image | |
BRC No. | RBRC05535 |
Type | Transgene |
Species | Mus musculus |
Strain name | C3H.C3B6-Tg(HTLV-I/LTR-pX)647Yiw |
Former Common name | C3-HTLV-I/pX Tg#647 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C3H/HeNSlc |
Appearance | |
Strain development | Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1991. Transgene was injected into the pronuclei of B6C3F1 fertilized eggs. C3H background. |
Strain description | Transgenic mice having env-pX region of human T cell leukemia virus type-I (HTLV-I). About 40 % of Tg mice develop chronic arthritis resembling rheumatoid arthritis. C3H background. |
Colony maintenance | Carrier x Noncarrier [or Crossing to C3H/HeNSlc] |
References | Science, 253, 1026-1028 (1991). 1887217 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HTLV-Ihuman T cell leukemia virus type-IUNHTLV-I |
Ordering Information | |
---|---|
Donor DNA | human T cell leukemia virus type-I (HTLV-I) LTR, human T cell leukemia virus type-I (HTLV-I) env-pX region |
Research application | Immunology and Inflammation Research Mouse Models for Human Disease |
Specific Term and Conditions | Please obtain the written consent from Professor Yoichiro Iwakura(iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science)for the use. |
Depositor | Yoichiro Iwakura (The University of Tokyo) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |