Strain Information | |
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Image | |
BRC No. | RBRC05548 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | SLW |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Tetsuo Kunieda, Faculty of Agriculture, Okayama University. Spontaneous mutation arose in ddY mouse colony. The mutant mouse was crossed with C57BL/6J, and maintained by sister-brother maintaining. |
Strain description | Short-limbed dwarfism, SLW mice. Spontaneous mutation arose in ddY mouse colony. Homozygous mice show dwarfism and most of them die before weaning. A 7-base deletion was identified in exon 8 of the Npr2 gene, resulting in a frameshift and premature termination codon appearance. |
Colony maintenance | Heterozygote x Wild-type |
References | J. Hered., 98, 575-580 (2007). 17728275 Am. J. Pathol., 177, 822-888 (2010). 20616347 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Am. J. Pathol., 177, 822-888 (2010). Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR. |
Depositor | Tetsuo Kunieda (Okayama University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Live mouse (3 to 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |