Strain Data Sheet
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Data update: May 20, 2019
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RBRC No. RBRC05551  
Type Targeted Mutation and TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(Aicda-cre)9Mbu Gt(ROSA)26Sor<tm1Hjf>  
Former Common name Aicda-cre/rosa-tdRFP, B6-AicdaCre/ROSA26-tdRFP  
H-2 Haplotype No Data  
ES cell line AK7 [129S4/SvJaeSor]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hitoshi Nagaoka, Graduate School of Medicine, Kyoto University. Rosa-tdRFP : Hans Jorg Fehling, Institute of Immunology, University Clinics Ulm. Aicda-cre : Meinrad Busslinger. Research Institute of Molecular Pathology.  
Strain description This strain has AID-Tg (Tg(Aicda-cre)9Mbu) and ROSA26 tdRFP reporter (Gt(ROSA)26Sor<tm1Hjf>) alleles.  
Colony maintenance Tg : Carrier x Carrier ; ROSA26 : Homozygote x Homozygote  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Gt(ROSA)26Sor  
Symbol name gene trap ROSA 26, Philippe Soriano  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 2 Symbol GH  
Symbol name Growth hormone polyA (Bovine)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 3 Symbol RFP  
Symbol name Red Fluorescent Protein (Discosoma sp.)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 4 Symbol SA  
Symbol name Splice acceptor (adenovirus)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 5 Symbol lox2272  
Symbol name mutant lox sequence  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 6 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 7 Symbol No Data  
Symbol name SV40 nuclear localization sequence  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 8 Symbol CD2 (human)  
Symbol name CD2 (human)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 9 Symbol Ires  
Symbol name internal ribosomal entry site (EMCV)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 10 Symbol poly A  
Symbol name SV40 polyadenylation site  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse Aicda promoter  
 11 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References Eur J Immunol. 2007 Jan;37(1):43-53.
Immunity. 2008 Jun;28(6):751-62.
  
Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.
Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.
Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.
Research applications Fluorescent Proteins/lacZ System  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature designated by the DEPOSITOR is requested. PLoS One. 2011 6(12):e29141.
2) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.
3) The BIOLOGICAL RESOURCE contains Tg(Aicda-re)9Mbu and Gt(ROSA)26Sortm1Hjf. Before executing the MTA between RIKEN BRC and the RECIPIENT, the RECIPIENT shall contact Dr. Meinrad Busslinger, Research Institute of Molecular Pathology and shall execute the material transfer agreement with Research Institute of Molecular Pathology to use Tg(Aicda-cre)9Mbu. The RECIPIENT shall obtain the prior written consent of Dr. Hans Joerg Fehling, Institute of Immunology, University Clinics Ulm to use Gt(ROSA)26Sortm1Hjf.  
Additional information
 1 Honjo Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Honjo, Tasuku (Graduate School of Medicine, Kyoto University)  Honjo, Tasuku 
Strain Status /
Availability
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