Strain Data Sheet
Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC05557  
Type Spontaneous Mutation  
Species Mus musculus  
Strain name B6J.MSM-Hiomt<MSM>  
Former Common name B6- Hiomt  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Takaoki Kasahara, RIKEN Brain Science Institute and Shigeharu Wakana, RIKEN BioResource Center in 2011. This congenic strain was generated by backcrossing to C57BL/6J from MSM/Ms.  
Strain description C57BL/6J congenic strain having Hiomt gene derived from Japanese wild-derived inbred mice, MSM/Ms. Melatonin synthesis requires enzymes encoded by Aanat and Hiomt genes. B6J.MSM-Aanat<MSM> Hiomt<MSM> (RBRC05503), B6J.MSM-Aanat<MSM> (RBRC05556), B6J.MSM-Hiomt<MSM> (RBRC05557).  
Colony maintenance Homozygote x Homozygote  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Asmt  
Symbol name acetylserotonin O-methyltransferase  
Chromosome UN  
Common name Hiomt  
Symbol description No Data  
References Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6412-7. Epub 2010 Mar 22.  
Genetic variation of melatonin productivity in laboratory mice under domestication.
Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.  
Additional information
 1 Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Kato, Tadafumi (RIKEN Center for Brain Science)  Kato, Tadafumi 
Strain Status /
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