Strain Information | |
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Image | |
BRC No. | RBRC05558 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | 129(Cg)-Rax<tm1.1Tfur> |
Former Common name | 129-Rax floxed |
H-2 Haplotype | |
ES Cell line | TC1 [129S6/SvEvTac] |
Background strain | 129S6/SvEvTac |
Appearance | |
Strain development | Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2006. 129 background. A Frt-flanked PGK-neo selection cassette was removed by crossing with FLP1 mice (B6;SJL-Tg(ACTFLPe)9205Dym/J). |
Strain description | Rax gene floxed mice. Exons 1 and 2 of the Rax gene were flanked by loxP sites. Conditional Rax deficient mice can be generated by crossing with tissue-specific Cre mice. |
Colony maintenance | Homozygote x Homozygote [or Crossing to 126S6/SvEvTac] |
References | J. Neurosci., 31, 16792-16807 (2011). 22090505 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site18Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP |
Ordering Information | |
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Donor DNA | Bacteriophage P1 loxP sites, Saccharomyces cerevisiae frt site, mouse Rax genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 31, 16792-16807 (2011).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University). |
Depositor | Takahisa Furukawa (Osaka Bioscience Institute) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |