Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC05559  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(Crx-cre/ERT2)1Tfur  
Former Common name 129S6;B6C3-Tg(Crx-cre/ERT2)1Tfur, 129-CrxCreERT2, 129-CrxCreER Tg  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2008. The transgene was injected into the pronuclei of B6C3F1 fertilized eggs.  
Strain description Crx-creERT2 transgenic mice. This transgenic mouse expresses tamoxifen-inducible cre recombinase gene in retinal photoreceptor cells and progenitor cells under the control of the mouse Crx promoter.  
Colony maintenance Carrier x Noncarrier [C57BL/6NCrlCrlj]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol ERT2  
Symbol name estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 2 Symbol polyA  
Symbol name SV40 polyA signal  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter Crx2K promoter  
 3 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Neurosci., 31, 16792-16807 (2011).
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).  
Additional information
 1 Mouse of the Month May 2013  
 2 Genotyping protocol <PCR>  
Depositor Furukawa, Takahisa (Osaka Bioscience Institute)  Furukawa, Takahisa 
Strain Status /
Availability
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