Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC05649  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129S4-Plin5<tm1Tosu>/Rbrc  
Former Common name B6-Plin5 KO, B6.129S4-Plin5<tm1>  
H-2 Haplotype No Data  
ES cell line J1 [129S4/SvJae]  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain description Plin5 perilipin 5 gene knockout mice. Exons 2 to 4 were replaced with a floxed PGK-neo cassette. In homozygous mutant mice, heart lipid droplets were absent and the activity of fatty acid oxidation was increased.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol GH  
Symbol name Growth hormone polyA (Bovine)  
Chromosome 17  
Common name No Data  
Symbol description No Data  
 2 Symbol Plin5  
Symbol name perilipin 5  
Chromosome 17  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 17  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 17  
Common name neo; neomycin;  
Symbol description No Data  
References J Biol Chem. 2006 May 19;281(20):14232-40. Epub 2006 Mar 29.

  
MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha.
MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha.
MLDP, a novel PAT family protein localized to lipid droplets and enriched in the heart, is regulated by peroxisome proliferator-activated receptor alpha.
Research applications Cardiovascular Research,
Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Biol. Chem., 287, 23852-23863 (2012).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Osumi, Takashi (University of hyogo)  Osumi, Takashi 
Strain Status /
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