Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC05703  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6;129S4-Gt(ROSA)26Sor<tm1.1Tiw>  
Former Common name ROSA-ERAI-LUCdNeo, B6-ROSA26/ERAI-LUCdNeo  
H-2 Haplotype No Data  
ES cell line RF8 [129S4/SvJae]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Takao Iwawaki, Advanced Science Institute, RIKEN in 2006. RF8 ES cells derived from 129S4/SvJae were used. The neo cassette was removed by crossing with Gt(ROSA)26Sor<tm1(FLP1)Dym> mice.  
Strain description ERAI (ER stress-activated indicator) knock-in mice. Floxed STOP cassette and modified ERAI construct (HA-2xXBP1deltaDBD(anATG)-LUC-F) were inserted into the Gt(ROSA)26Sor locus. The ERAI expression can be generated by crossing with tissue-specific Cre mice.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Gt(ROSA)26Sor  
Symbol name gene trap ROSA 26, Philippe Soriano  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 2 Symbol FLAG  
Symbol name FLAG tag (synthetic)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 3 Symbol Frt  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 4 Symbol HA  
Symbol name human influenza virus HA (hemagglutinin) tag sequence  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 5 Symbol XBP1  
Symbol name X-box binding protein 1  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 6 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 6  
Common name No Data  
Symbol description No Data  
 7 Symbol luc  
Symbol name luciferase (firefly)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
References   
Research applications Cell Biology Research,
Cre/loxP system,
FLP/frt system,
Fluorescent Proteins/lacZ System  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. J. 425, 117-125 (2010).  
Additional information
 1 Mouse of the Month Jan 2013  
Depositor Iwawaki, Takao (Medical research institute,kanazawa medical university)  Iwawaki, Takao 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM