Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC05752  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129-Ttll10<tm1Seto>  
Former Common name TTLL10 KO, B6-Ttll10 KO  
H-2 Haplotype No Data  
ES cell line RENKA [C57BL/6NCrlCrlj]  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Medical Photonics Research Center, Hamamatsu University School of Medicine in 2008. The mutant mice were crossed to C57BL/6J.  
Strain description Ttll10 gene knockout mice. A part of exon 2 to exon 6 were replaced with a neo cassette.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Ttll10  
Symbol name tubulin tyrosine ligase-like family, member 10  
Chromosome 4  
Common name No Data  
Symbol description No Data  
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 4  
Common name neo; neomycin;  
Symbol description No Data  
References FEBS Lett. 2008 Apr 2;582(7):1129-34. Epub 2008 Mar 10.  
TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1.
Research applications Cell Biology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for-profit institution for a not-for-profit research. Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT must contact the DEPOSITOR prior to publishing the research results obtained by use of the BIOLOGICAL RESOURCE. The RECIPIENT must contact in advance the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT must not distribute the BIOLOGICAL RESOURCE and the derivatives to third parties.  
Additional information
 1 No Data  
Depositor Setou, Mitsutoshi (Hamamatsu University School of Medicine)  Setou, Mitsutoshi 
Strain Status /
Availability
(Expected delivery)

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