Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC05808  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129P2-Aldh2<tm1Kaw>  
Former Common name Aldh2KO  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Kyoko Kitagawa and Toshihiro Kawamoto, University of Occupational and Environmental Health in 1998. E14 ES cells were used. The mutant mice were backcrossed to C57BL/6 over 7 times.  
Strain description Aldh2 gene knockout mice. A termination codon and a neomycin selection cassette was inserted into exon 3 of Aldh2 gene.  
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6JJcl] Homozygous mutant mice are viable and fertile.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol No Data  
Symbol name SV40 Poly A signal  
Chromosome 5  
Common name No Data  
Symbol description No Data  
 2 Symbol Aldh2  
Symbol name aldehyde dehydrogenase 2, mitochondrial  
Chromosome 5  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 3 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 5  
Common name No Data  
Symbol description No Data  
References


  



Research applications Metabolism Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.  
Additional information
 1 Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Nakayama, Keiichi (Medical institute of bioregulation, Kyushu University)  Nakayama, Keiichi 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM