Strain Information | |
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Image | |
BRC No. | RBRC05841 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(hOX-tTA)1Ahky |
Former Common name | Orexin-tTA, B6-hOX-tTA Tg, C57BL/6-Tg(hOX-tTA)1Ahky |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Dr. Akihiro Yamanaka, National Institute for Physiological Sciences in 2008. C57BL/6J background. |
Strain description | Orexin neuron specific tTA transgenic mice. |
Colony maintenance | Carrier x Carrier [or Crossing to C57BL/6JJcl]Tg homozygous and hemizygous mice are viable and fertile. |
References | Sleep, 36(9):1391-404 (2013). 23997373 Neurosci. Res., 2012 Jul 31. pii: S0168-0102(12)00144-7. 22868039 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)UNtTAE. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domainhuman orexin (hypocretin) promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyAUN |
Ordering Information | |
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Donor DNA | human orexin (hypocretin) promoter, E. coli Tet repressor (tetR), HSV VP16 activation domain, SV40 polyA |
Research application | Neurobiology Research Tet system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Akihiro Yamanaka (Nagoya University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |