Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: May 20, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC05846  
Type TransgeneCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(Tph2-tTA)1Ahky  
Former Common name Tph2-tTA, B6-Tph2-tTA Tg  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Dr. Akihiro Yamanaka, National Institute for Physiological Sciences in 2010. Tph2 locus of the BAC RP23-112F24 clone was replaced with tTA.  
Strain description Serotonin neuron neuron specific tTA BAC transgenic mice.  
Colony maintenance Carrier x Carrier [or Crossing to C57BL/6JJcl]
Tg homozygous and hemizygous mice are viable and fertile.  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Frt  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome UN  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome UN  
Common name No Data  
Symbol description No Data  
Promoter mouse tryptophan hydroxylase 2 promoter  
 3 Symbol tTA  
Symbol name tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)  
Chromosome UN  
Common name E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain  
Symbol description No Data  
References Unpublished  
Research applications Cre/loxP system,
FLP/frt system,
Neurobiology Research,
Tet system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Yamanaka, Akihiro (Research Institute of Environmental Medicine Nagoya university)  Yamanaka, Akihiro 
Strain Status /
Availability
(Expected delivery)

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