Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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  Mouse Marking
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RBRC No. RBRC05885  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.Cg-Vdr<tm1Ska>  
Former Common name B6-Vdr KO  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Dr. Shigeaki Kato, Institute of Molecular and Cellular Biosciences, University of Tokyo. C57BL/6 and CBA mixed.  
Strain description Vitamin D receptor gene knockout mice. 1.1kb region containing exon 2 of Vdr was replaced with a neomycin resistance cassette. Homozygous mutant mice show vitamin D dependent rickets type II.  
Colony maintenance Heterozygote x Wild-type  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Vdr  
Symbol name vitamin D receptor  
Chromosome 15  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 15  
Common name neo; neomycin;  
Symbol description No Data  
References
  

Research applications Developmental Biology Research,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Nat. Genet., 16, 391-396 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Shigeaki Kato, uskato0525@gmail.com).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Jishage, Kou-ichi (Chugai Pharmaceutical Co.,Ltd.)  Jishage, Kou-ichi 
Strain Status /
Availability
(Expected delivery)

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