Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
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Figure
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RBRC No. RBRC05889  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129P2-Dpysl2<tm1Gosh>  
Former Common name CRMP2KI  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Naoya Yamashita, Yokohama City University Graduate School of Medicine, Katsuhiko Mikoshiba, RIKEN Brain Science Institute in 2006. A floxed neo cassette remains inserted upstream of exon 13. The mutant mice were backcrossed to C57BL/6 over six times.  
Strain description CRMP2 (Dpysl2) Ser522Ala mutation knock-in mice.  
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6J(Crlj)]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Dpysl2  
Symbol name dihydropyrimidinase-like 2  
Chromosome 14  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 14  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 14  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 14  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system,
Neurobiology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research requiring co-authorship of RIKEN CBS Katsuhiko Mikoshiba, Ph.D. (DEPOSITOR). Waseda University Center for Advanced Biomedical Sciences Yoshio Goshima, Ph.D., Yokohama City University Yoshiro Goshima, Ph.D. in publication.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Mikoshiba, Katsuhiko (RIKEN Center for Brain Science)  Mikoshiba, Katsuhiko 
Strain Status /
Availability
(Expected delivery)

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