Strain Data Sheet
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Data update: Jul 19, 2019
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RBRC No. RBRC05910  
Type TransgeneCartagena  
Species Mus musculus  
Strain name C.C3-Tg(Mt1-Il5)6Ato  
Former Common name IL-5 transgenic mice  
H-2 Haplotype No Data  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Generated by Kiyoshi Takatsu, Kumamoto University Medical School. The transgene was injected into the pronuclei of C3H fertilized eggs. C57BL/6 (RBRC01908) and BALB/c (RBRC05910) background (Developed by Institute of Medical Science, University of Tokyo), NZW background (RBRC01200) (Developed by Juntendo University School of Medicine).  
Strain description Mt1-Il5 transgenic mice. These transgenic mice express mouse IL-5 under the control of the Mt1 promoter.  
Colony maintenance Carrier x Carrier (Homozygous x Homozygote) Tg mice show no obvious abnormality.  
Health Report No Data  
Gene Details
Promoter mouse metallothionein promoter  
 1 Symbol Il5  
Symbol name interleukin 5  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References J Exp Med. 1991 Feb 1;173(2):429-37.  
Transgenic mice expressing a B cell growth and differentiation factor gene (interleukin 5) develop eosinophilia and autoantibody production.
Research applications Immunology and Inflammation Research,
Metabolism Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
J. Exp. Med., 173, 429-437 (1991).  
Additional information
 1 No Data  
Depositor Arita, Makoto (The University of Tokyo)  Arita, Makoto 
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