Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
Figure
  Order
RBRC No. RBRC05917  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129S2-Mir200b<tm1.1Osb> Mir429<T30C>  
Former Common name miR-DKO, Mir200b<tm1.1Osb> Mir429<T30COsb>/39  
H-2 Haplotype No Data  
ES cell line D3 [129S2/SvPas]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hidetoshi Hasuwa and Masaru Okabe, Research Institute for Microbial Diseases, Osaka University in 2003. The mutant mice were backcrossed to C57BL/6N over 7 times.  
Strain description miR200b knockout mice having a point mutation in miR429. Homozygous mutant females show a severe infertility due to abnormal ovulation.  
Colony maintenance Heterozygote x Wild-type[C57BL/6NJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Mir200b  
Symbol name microRNA 200b  
Chromosome 4  
Common name No Data  
Symbol description No Data  
 2 Symbol Mir429  
Symbol name microRNA 429  
Chromosome 4  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 4  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Science, 341, 71-73 (2013).
RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (http://www.uic.osaka-u.ac.jp/en/index.html). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.  
Additional information
 1 Lab HP  
 2 Genotyping protocol <PCR>  
Depositor Ikawa, Masahito (Osaka university)  Ikawa, Masahito 
Strain Status /
Availability
(Expected delivery)

back Back
RIKEN BioResource Research Center

English page click here ANIMAL SEARCH SYSTEM