Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC05922  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6;129P2-Eed<tm1(I363M)Homy>  
Former Common name IEed I363M K  
H-2 Haplotype No Data  
ES cell line E14 [129P2/OlaHsd]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2012. E14 ES cells (129P2/OlaHsd) were used. The mutant mice were crossed to C57BL/6 mice. Neomycin selection cassette was removed by crossing with Cre mice.  
Strain description Eed I363M mutant knock-in mice. I363M mutation in the EED gene was found from patients with myelodysplastic syndromes.  
Colony maintenance Heterozygote x Wild-type [C57BL/6NCrlCrlj]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Eed  
Symbol name embryonic ectoderm development  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 7  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system,
Developmental Biology Research,
Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.  
Additional information
 1 No Data  
Depositor Honda, Hiroaki (Tokyo Women's Medical University)  Honda, Hiroaki 
Strain Status /
Availability
(Expected delivery)

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