Strain Data Sheet
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Data update: Jul 19, 2019
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC05954  
Type Targeted Mutation and Chromosomal AberrationCartagena  
Species Mus musculus  
Strain name B6.129S7-Dp(7Herc2-Mkrn3)1Taku  
Former Common name B6-Dp(7C)  
H-2 Haplotype No Data  
ES cell line AB2.2 [129S7/SvEvBrd-Hprt]  
Background strain C57BL/6JJcl  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Toru Takumi, Osaka Bioscience Institute and Allan Bradley, The Wellcome Trust Sanger Institute in 2004. The mutant mice were backcrossed to C57BL/6J over 20 times.  
Strain description Chromosome-engineered mouse strain having a 6.3 Mb duplication of mouse chromosome 7 mirroring the human chromosome 15q11-13 duplication.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol HPRT  
Symbol name hypoxanthine guanine phosphoribosyl transferase (human)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 2 Symbol Herc2  
Symbol name HECT and RLD domain containing E3 ubiquitin protein ligase 2  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 3 Symbol Mkrn3  
Symbol name makorin, ring finger protein, 3  
Chromosome 7  
Common name No Data  
Symbol description No Data  
 4 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Promoter K14 promoter  
 5 Symbol agouti  
Symbol name No Data  
Chromosome 7  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system,
Developmental Biology Research,
Mouse Models for Human Disease,
Neurobiology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.  
Additional information
 1 Mouse of the Month Apr 2015  
 2 Genotyping protocol <PCR>  
Depositor Takumi, Toru (RIKEN Center for Brain Science)  Takumi, Toru 
Strain Status /
Availability
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