Strain Information | |
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Image | |
BRC No. | RBRC05954 |
Type | Targeted Mutation and Chromosomal Aberration |
Species | Mus musculus |
Strain name | B6.129S7-Dp(7Herc2-Mkrn3)1Taku |
Former Common name | B6-Dp(7C) |
H-2 Haplotype | |
ES Cell line | AB2.2 [129S7/SvEvBrd-Hprt<b-m2>] |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Toru Takumi, Osaka Bioscience Institute and Allan Bradley, The Wellcome Trust Sanger Institute in 2004. The mutant mice were backcrossed to C57BL/6J over 20 times. |
Strain description | Chromosome-engineered mouse strain having a 6.3 Mb duplication of mouse chromosome 7 mirroring the human chromosome 15q11-13 duplication. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Cell, 137, 1235-1246 (2009). 19563756 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HPRThypoxanthine guanine phosphoribosyl transferase (human)7HPRT Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP |
Ordering Information | |
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Donor DNA | human HPRT genomic DNA, human Keratin14 genomic DNA, mouse Agouti genomic DNA, mouse Tyrosinase genomic DNA, Phage P1 loxP site |
Research application | Cre/loxP system Developmental Biology Research Mouse Models for Human Disease Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. |
Depositor | Toru Takumi (RIKEN) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Apr 2015 |
BRC mice in Publications |
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No Data |