Strain Information | |
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Image | |
BRC No. | RBRC05979 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | ICR;129-Hes1<tm1Fgu> |
Former Common name | Hes1 KO ; Hes1 KO |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Developed by Ryoichiro Kageyama, Kyoto University/IGBMC in 1994. R1 ES cells were used. The mutant mice were crossed to ICR. |
Strain description | Hes1 gene knockout mice. The first tree exons were replaced with a PGK-neo cassette. |
Colony maintenance | Heterozygote x Wild-type [or Crossing to Slc:ICR] |
References | Genes Dev., 9(24):3136-3148 (1995). 8543157 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)16mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Hes1 genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev. 1995 9(24):3136-48.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Itaru Imayoshi and Ryoichiro Kageyama (Kyoto University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering: |
BRC mice in Publications |
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No Data |