Strain Information | |
---|---|
Image | |
BRC No. | RBRC05983 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | ICR.Cg-Hes7<tm1Kag> |
Former Common name | Hes7 KO ; Hes7 KO/lacZ |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2001. TT2 ES cells were used. The mutant mice were crossed to ICR. |
Strain description | Most of the coding region was replaced with a IRES-lacZ-PGK-neo cassette. Most homozygous mutant mice die within a few hours of birth. |
Colony maintenance | Heterozygote x Wild-type [or Crossing to Slc:ICR] |
References | Genes Dev. 2001 15(20):2642-7. 11641270 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Iresinternal ribosomal entry site (EMCV)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
---|---|
Donor DNA | EMCV (Encephalomyocarditis virus) internal ribosomal entry site (IRES), beta galactosidase (E. coli), mouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Hes7 genomic DNA |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev. 2001 15(20):2642-7.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Itaru Imayoshi and Ryoichiro Kageyama (Kyoto University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |