Strain Data Sheet
ANIMAL SEARCH SYSTEM
Data update: Jun 20, 2019
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RBRC No. RBRC05983  
Type Targeted Mutation CongenicCartagena  
Species Mus musculus  
Strain name ICR.Cg-Hes7<tm1Kag>  
Former Common name Hes7 KO ; Hes7 KO/lacZ  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2001. TT2 ES cells were used. The mutant mice were crossed to ICR.  
Strain description Most of the coding region was replaced with a IRES-lacZ-PGK-neo cassette. Most homozygous mutant mice die within a few hours of birth.  
Colony maintenance Heterozygote x Wild-type [or Crossing to Slc:ICR]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Hes7  
Symbol name hairy and enhancer of split 7 (Drosophila)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
 2 Symbol Ires  
Symbol name internal ribosomal entry site (EMCV)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
 3 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
References   
Research applications Fluorescent Proteins/lacZ System  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genes Dev. 2001 15(20):2642-7.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).  
Additional information
 1 No Data  
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University)  Kageyama, Ryoichiro 
Strain Status /
Availability
(Expected delivery)

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