Strain Data Sheet
Data update: Aug 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC05993  
Type Targeted Mutation CongenicCartagena  
Species Mus musculus  
Strain name ICR.Cg-Hes7<tm3Kag>  
Former Common name Hes7 intron-les ; Hes7 KO/intronless  
H-2 Haplotype No Data  
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2007. TT2 ES cells were used. The mutant mice were crossed to ICR.  
Strain description Intronless He7 mice. The intron sequence of Hes7 were removed. The The floxed neo cassette was removed by transient expresion of cre recombinase.  
Colony maintenance Heterozygote x Wild-type [or Crossing to Slc:ICR]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Hes7  
Symbol name hairy and enhancer of split 7 (Drosophila)  
Chromosome 11  
Common name No Data  
Symbol description No Data  
 2 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 11  
Common name No Data  
Symbol description No Data  
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 2011 108(8):3300-5.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: ). (No approval form (Form D) is necessary).  
Additional information
 1 No Data  
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University)  Kageyama, Ryoichiro 
Strain Status /
(Expected delivery)

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