Strain Information | |
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Image | |
BRC No. | RBRC06044 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Hes3<tm1Kag> |
Former Common name | B6-Hes3 KO ; B6-Hes3 KO |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2000. TT2 ES cells were used. The mutant mice were crossed to C57BL/6 for 6 times. |
Strain description | Hes3 gene knockout mice. The whole coding region of Hes3 was replaced with a lacZ-neo cassette. Homozygous mutant mice are fertile with no obvious defects. |
Colony maintenance | Homozygote x Homozygote [C57BL/6JJcl] |
References | EMBO J. 2001 20(16):4454-66. 11500373 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | EMCV (Encephalomyocarditis virus) internal ribosomal entry site (IRES), beta-galactosidase (E. coli), mouse phosphoglycerate kinase promoter (PGK promoter), Neo (E. coli), mouse Hes3 genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J. 2001 20(16):4454-66.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Itaru Imayoshi and Ryoichiro Kageyama (Kyoto University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |