Strain Data Sheet

RBRC06182

Strain Information

Image
BRC No.RBRC06182
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S2.129(B6)-Thrb<tm1Olc>/Sasu
Former Common nameＴＲβ-/-, 129-Thrb KO
H-2 Haplotype
ES Cell lineENS [129/Sv]
Background strain129S2/SvPas
Appearance
Strain developmentDeveloped by Olivier Chassande and Jacques Samarut, Ecole Normale Superieure de Lyon. ENS ES cells derived from 129/Sv were used.
Strain descriptionThra gene knockout mice. Exons 5 through 7 were replaced with a lacZ-neo cassette.
Colony maintenanceHomozygote x Homozygote
ReferencesEMBO J., 18, 623-631 (1999). 9927422

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Thrbthyroid hormone receptor beta14Thrb<tm1Olc>targeted mutation 1, Olivier Chassande

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
lacZbeta-galactosidase (E. coli)14

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)14

Ordering Information

Donor DNAE. coli Neomycin resistance gene, E. coli beta-galactosidase, mouse Thra genomic DNA
Research applicationFluorescent Proteins/lacZ System
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorSatoru Suzuki (Fukushima Medical University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data