Strain Information | |
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Image | |
BRC No. | RBRC06190 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | D2;129-Myod1<tm1Jae> |
Former Common name | MyoD-KO, D2-Myod1 KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Rudolf Jaenisch, Whitehead Institute and Department of Biology Massachusetts Institute of Technology Cambridge. J1 ES cells were used. The mutant mice were maintained by Naohiro Hashimoto, National Center for Geriatrics and Gerontology. 129 and DBA/2 mixed background. |
Strain description | MyoD1 gene knockout mice. The Myod1 promoter, exon 1 and half of intron 1 were replaced with a a neomycin cassette. |
Colony maintenance | Homozygote x Homozygote |
References | Cell, 71, 383-390 (1992). 1330322 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (Klebsiella pneumoniae)7mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse Myod1 genomic DNA, Klebsiella pneumoniae neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter) |
Research application | Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell, 71, 383-390 (1992). |
Depositor | Naohiro Hashimoto (National Center for Geriatrics and Gerontology) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |