Strain Data Sheet
Data update: Jun 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC06190  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name D2;129-Myod1<tm1Jae>  
Former Common name MyoD-KO, D2-Myod1 KO  
H-2 Haplotype No Data  
Background strain No Data  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Rudolf Jaenisch, Whitehead Institute and Department of Biology Massachusetts Institute of Technology Cambridge. J1 ES cells were used. The mutant mice were maintained by Naohiro Hashimoto, National Center for Geriatrics and Gerontology. 129 and DBA/2 mixed background.  
Strain description MyoD1 gene knockout mice. The Myod1 promoter, exon 1 and half of intron 1 were replaced with a a neomycin cassette.  
Colony maintenance Homozygote x Homozygote  
Health Report
Gene Details
Promoter No Data  
 1 Symbol Myod1  
Symbol name myogenic differentiation 1  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (Klebsiella pneumoniae)  
Chromosome 7  
Common name No Data  
Symbol description No Data  
Research applications Mouse Models for Human Disease  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Cell, 71, 383-390 (1992).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Hashimoto, Naohiro (National Institute for Longevity Sciences)  Hashimoto, Naohiro 
Strain Status /
(Expected delivery)

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