Strain Information | |
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Image | |
BRC No. | RBRC06329 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Ly6a-KDM1A*v2)3Fscr |
Former Common name | LSD1 Tg#3, B6-Ly6A-KDM1A/v2 Tg#3 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Taeko Wada, Center for Molecular Medicine, Jichi Medical University in 2012. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs. Line 3 (RBRC06329), Line 6 (R BRC06330). |
Strain description | Ly6A-KDM1A transgenic mice. These mice express the human KDM1A (LSD1) (transcript variant 2) under the control of the mouse Ly6A promoter. Tg mice show no obvious abnormality. Under investigation (details unknown). |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJmsSlc] |
References | Nat Med. 11, 605-611, (2012). 22406747 Cancer Cell. 21(4):473-487, U, (2012). 22464800 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter KDM1Alysine (K)-specific demethylase 1A (human)UNKDM1Amouse Sca-1(Ly6A) promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)UN Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signalUN |
Ordering Information | |
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Donor DNA | E. coli Neomycin resistance gene, Human LSD1(KDM1A)gene cDNA, mouse Sca-1(Ly6A) promoter, SV40 PolyA signal |
Research application | Cancer Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) |
Depositor | Yusuke Furukawa (Jichi Medical University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |