Strain Information | |
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Image | |
BRC No. | RBRC06331 |
Type | Gene Trap |
Species | Mus musculus |
Strain name | B6;129-Dtx4<Gt(431E3)Cmhd> |
Former Common name | Dtx4 KO, B6-Dtx4 Gt |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Developed by Naifang Lu, Athanasia Spandidos and Brian Seed, Massachusetts General Hospital. The gene trapped mice were generated by using a CMHD-GT_431-E3-3 ES clone from Canadian Mouse Mutant Repository. C57BL/6 and 129 mixed background. |
Strain description | Dtx4 gene trapped mice (originated from Canadian Mouse Mutant Repository, Vector: pNMDi4, CMHD-GT_431-E3-3 clone. Homozygous mutant mice show no obvious abnormality. Under investigation (details unknown). |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6NTac] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Dtx4deltex 4 homolog (Drosophila)19Dtx4<Gt(431E3)Cmhd>gene trap 431E3, Centre for Modeling Human Disease Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)19GH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Hprtmouse Hprt splice donor (SD)19Hprt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SAhuman adenovirus type 3/5 SA (splice acceptor)19SA Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter VenusYellow Fluorescent Protein (Aequorea victoria)19Venus Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP19loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP19loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)19mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Human adenovirus type 3/5 SA (splice acceptor), flexible linker (FL), jellyfish Venus, P1 phage loxP, Eukaryotic translation initiation factor 3 subunit 7, BGH polyA, mouse PGK promoter, E. coli neomycin resistance gene, mouse Hprt SD (splice donor) |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE containing Venus, an acknowledgment to Dr. Atsushi Miyawaki and a citation of the following literature(s) designated by the DEPOSITOR are requested. Nat. Biotechnol., 20, 87-90 (2002). |
Depositor | Brian Seed (Massachusetts General Hospital) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |