Strain Information | |
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Image | |
BRC No. | RBRC06388 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Fbxl21<tm1Kei> |
Former Common name | Fbxl21 KO, B6-bxl21 KO |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Keiichi Nakayama, Medical Institute of Bioregulation, Kyushu University. E14 ES cells were used. The mutant mice were crossed to C57BL/6J (N7 generations). |
Strain description | Fbxl21 gene knockout mice. Exons 4 and 5 were replaced with an IRES-lacZ/neo cassette. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6JJcl] |
References | Cell, 152, 1106-1118 (2013). 23452856 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Fbxl21F-box and leucine-rich repeat protein 2113Fbxl21<tm1Kei>targeted mutation 1, Keiichi I Nakayama Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)13 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)13 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP13loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP13loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signal13 |
Ordering Information | |
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Donor DNA | E. coli Neomycin resistance gene, mouse phosphoglycerate kinase promoter, SV40 polyA signal, ECMV internal ribosomal entry site (ires), E. coli lacZ, phage P1 loxP |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System Metabolism Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. |
Depositor | Keiichi Nakayama (Kyushu University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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No Data |