Strain Information | |
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Image | |
BRC No. | RBRC06403 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Cdkn1c<tm1Kat> |
Former Common name | p57 KO, B6-Cdkn1c KO |
H-2 Haplotype | |
ES Cell line | E14 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | Developed by Keiichi Nakayama, Medical Institute of Bioregulation, Kyushu University. E14 ES cells were used. The mutant mice were crossed to C57BL/6J. |
Strain description | p57 gene knockout mice. Exons 1 to 3 and a part of exon 4 were replaced with a PGK-neo cassette. Paternal imprinting gene. |
Colony maintenance | Heterozygote (male) x Wild-type (female) [C57BL/6JJcl] |
References | J. Biochem., 127, 73-83 (2000). 10731669 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)7Cdkn1c<tm1Kat>targeted mutation 1, Katsuhiko Takahashi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signal7 |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promoter, E. coli Neomycin resistance gene, SV40 polyA signal, mouse Cdkn1c genomic DNA |
Research application | Cell Biology Research Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. |
Depositor | Keiichi Nakayama (Kyushu University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
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BRC mice in Publications |
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