Strain Data Sheet

RBRC06403

Strain Information

Image
BRC No.RBRC06403
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Cdkn1c<tm1Kat>
Former Common namep57 KO, B6-Cdkn1c KO
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Keiichi Nakayama, Medical Institute of Bioregulation, Kyushu University. E14 ES cells were used. The mutant mice were crossed to C57BL/6J.
Strain descriptionp57 gene knockout mice. Exons 1 to 3 and a part of exon 4 were replaced with a PGK-neo cassette. Paternal imprinting gene.
Colony maintenanceHeterozygote (male) x Wild-type (female) [C57BL/6JJcl]
ReferencesJ. Biochem., 127, 73-83 (2000). 10731669

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Cdkn1ccyclin-dependent kinase inhibitor 1C (P57)7Cdkn1c<tm1Kat>targeted mutation 1, Katsuhiko Takahashi

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP7loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP7loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA signal7

Ordering Information

Donor DNAphage P1 loxP sites, mouse phosphoglycerate kinase promoter, E. coli Neomycin resistance gene, SV40 polyA signal, mouse Cdkn1c genomic DNA
Research applicationCell Biology Research
Cre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
DepositorKeiichi Nakayama (Kyushu University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP

BRC mice in Publications

No Data