Strain Information | |
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Image | |
BRC No. | RBRC06422 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | BALB/c-Scn1a<+/-> |
Former Common name | C.Dravet, BALB-Scn1a |
H-2 Haplotype | |
ES Cell line | |
Background strain | BALB/cCrSlc |
Appearance | |
Strain development | Developed by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology. |
Strain description | Scn1a spontaneous mutant (Dravet syndrome) mice arose in BALB/c. Heterozygous mice show heat-induced epileptic seizure. Homozygous mutant mice show severe myoclonic epilepsy in infancy, and die at around 3 weeks old. Under investigation. BALB/cCrSlc background (semicongenic) (RBRC06422). |
Colony maintenance | Heterozygote x Heterozygote [or Crossing to BALB/cCrSlc] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | Mouse Models for Human Disease Neurobiology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
Depositor | Yoshibumi Matsushima (Saitama Cancer Center) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |