Strain Data Sheet
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Data update: Jun 20, 2019
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RBRC No. RBRC06446  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name B6.129-Clmp<tm1Jwada>  
Former Common name B6-ACAM KO B6-Clmp KO  
H-2 Haplotype No Data  
ES cell line Not specified (ES cell)  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Jun Wada, Okayama University Graduate School of Medicine, Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo (Research Institute for Biomedical Sciences, Tokyo University of Science) in 2008. 129P2/OlaHsd derived ES cells were used to generate the mutant mice.  
Strain description ACAM (CLMP) gene knockout mice. Exons 3 and 4 of the ACAM gene was replaced with a floxed-neo cassette. Homozygous mutant mice of C57BL/6 background show a severe growth defect and die by about 6 weeks of age. Homozygous mutant mice of ICR background show and increased birth rate, but die by 14 weeks of age. C57BL/6 background (RBRC06446), ICR background (RBRC06447), B6/ICR mixed (RBRC06448).  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Clmp  
Symbol name CXADR-like membrane protein  
Chromosome 9  
Common name No Data  
Symbol description No Data  
 2 Symbol GH  
Symbol name Growth hormone polyA (Bovine)  
Chromosome 9  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 9  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 9  
Common name No Data  
Symbol description No Data  
References
  

Research applications Cre/loxP system  
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)  
Additional information
 1 No Data  
Depositor Wada, Jun (Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences)  Wada, Jun 
Strain Status /
Availability
(Expected delivery)

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