Strain Data Sheet
RBRC06533
Strain Information | |
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| Image | |
| BRC No. | RBRC06533 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | C57BL/6N-Tifab<tm1Csk> |
| Former Common name | DC-TIF KO, B6-Tifab KO |
| H-2 Haplotype | |
| ES Cell line | Not specified (ES cell) |
| Background strain | C57BL/6NCrlCrlj |
| Appearance | |
| Strain development | Developed by Kouji Matsushima, Graduate School of Medicine, University of Tokyo and Chugai Pharmaceutical Co, Ltd. C57BL/6N derived ES cells were used to generate the mutant mice. C57BL/6N background. |
| Strain description | DC-TIF (Tifab) gene knockout mice. A loxP-flanked neo cassette was inserted into the exon 3. Homozygous mutant mice show no obvious abnormality. |
| Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6N] |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter TifabTRAF-interacting protein with forkhead-associated domain, family member B13Tifab<tm1Csk>targeted mutation 1, Chugai Pharmaceutical Co, Ltd Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP13loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP13loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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| Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Phage P1 loxP, mouse Tifab genomic DNA |
| Research application | Cre/loxP system Immunology and Inflammation Research |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOUCE, the RECIPIENT shall obtain a written consent from the DEPOSITTOR and its co-developer (Dr. Kou-ichi Jishage: jishagekui@chugai-pharm.co.jp, Chugai Pharmaceutical Co., Ltd. and Professor Kouji Matsushima: koujim@rs.tus.ac.jp) and, if necessary, shall enter into a material transfer agreement with their institutes. |
| Depositor | Drs. Kouji Matsushima and Kou-ichi Jishage (The University of Tokyo/ Chugai Pharmaceutical Co., Ltd.) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |