Strain Data Sheet
RBRC06534
Strain Information | |
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| Image | |
| BRC No. | RBRC06534 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129S6-Fcrl6<tm1Csk> |
| Former Common name | NKIR KO, B6-Fcrl6 KO |
| H-2 Haplotype | |
| ES Cell line | Not specified (ES cell) |
| Background strain | |
| Appearance | |
| Strain development | Developed by Kouji Matsushima, Graduate School of Medicine, University of Tokyo and Chugai Pharmaceutical Co, Ltd. 129S6 derived ES cells were used to generate the mutant mice. C57BL/6 and 129 mixed background. |
| Strain description | NKIR (Fcrl6) gene knockout mice. From exon 3 to a part of exon 6 was replaced with a loxP-flanked neo cassette. Homozygous mutant mice show no obvious abnormality. |
| Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6JJcl] |
| References | |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)1mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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| Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Phage P1 loxP, mouse Fcrl6 genomic DNA |
| Research application | Cre/loxP system Immunology and Inflammation Research |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOUCE, the RECIPIENT shall obtain a written consent from the DEPOSITTOR and its co-developer (Dr. Kou-ichi Jishage: jishagekui@chugai-pharm.co.jp, Chugai Pharmaceutical Co., Ltd. and Professor Kouji Matsushima: koujim@rs.tus.ac.jp) and, if necessary, shall enter into a material transfer agreement with their institutes. |
| Depositor | Drs. Kouji Matsushima and Kou-ichi Jishage (The University of Tokyo/ Chugai Pharmaceutical Co., Ltd.) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |