Strain Data Sheet
Data update: Aug 20, 2019
Health Report   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC06558  
Type Chemically-induced Mutation  
Species Mus musculus  
Strain name B6(D2)-Smo<Rgsc2073>  
Former Common name SmoG457X, B6-Smo/G457X  
H-2 Haplotype No Data  
Background strain C57BL/6JJcl  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Shigeru Makino and Yoichi Gondo, RIKEN BioResource center. Generated by RIKEN ENU-based gene driven mutagenesis. The mutant mice were backcrossed to C57BL/6J.  
Strain description Smo gene G457X variant mice. Homozygous mutant mice die around E10.  
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]  
Health Report No Data  
Gene Details
Promoter No Data  
 1 Symbol Smo  
Symbol name smoothened homolog (Drosophila)  
Chromosome 6  
Common name No Data  
Symbol description No Data  
References Nat Rev Genet. 2008 Oct;9(10):803-10.  
Trends in large-scale mouse mutagenesis: from genetics to functional genomics.
Research applications Cancer Research,
Developmental Biology Research,
Neurobiology Research  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced).  
Additional information
 1 No Data  
Depositor Gondo, Yoichi (RIKEN, BioResource Center)  Gondo, Yoichi 
Strain Status /
(Expected delivery)

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